Abstract
The discovery, isolation, characterization, and some biological activities of N-formyl hydroxyaminoacetic acid, have been reported (4, 6). This compound is produced by a number of species of Penicillium with the best producers thus far belonging to the P. frequentans series (3). One may consider N-formyl hydroxyaminoacetic acid as an analogue of glycine in which a formyl and a hydroxyl substitute for the hydrogens on the amino nitrogen. It would be interesting to determine if Nformyl hydroxyamino derivatives of other amino acids are also produced. The studies reported herein are directed to this possibility as well as to basic prob'ems of the formation of N-formyl hydroxyaminoacetic acid, hereafter referred to as NFHAA.
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