Abstract

1. A method is described for the purification of Col-SK virus which makes use of adsorption on and elution from sheep red blood cells. 2. The ultraviolet adsorption spectrum of Col-SK virus is characteristic of nucleoproteins. 3. When large amounts of Col-SK virus are adsorbed on sheep red blood cells there occurs a decrease of electrophoretic mobility of the latter. This effect is not obtained with less than maximal amounts of virus. 4. Red cells from which the virus has been eluted move in the electrical field at the same rate as do normal red cells.

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