Abstract

The oncogenicity of the cultivated cells of C3H/He mouse salivary gland adenocarcinoma is strictly correlated with the presence of the viral particles (Bittner). From both a quantitative and a qualitative standpoint the growth of the implanted tumor is similar to that observed in vivo and completely different from the mammary gland tumor which is also produced by Bittner virus. After 180 days the viral particles disappear from the cell and thereafter the cells are no longer oncogenic when implanted in isogeneic hosts.

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