Abstract
Summary Three cases of congenital heart diseasemanifesting a complex which has been accounted for as a failure or delay in endocardial cushion development have been described anatomically and discussed. This discussion has tended to point to (1) the critical period in development of basic structural anomalies of the heart, (2) the anatomical and embryologic explanation of the three cases presented, and (3) the need of careful post-mortem examination of specimens, particularly in those cases where a history or suggestion of cardiac or cardiovascular irregularity has existed.
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