Abstract

1. 1. When two male mice fight to establish social rank, the subordinate exhibits marked splenomegaly, reticulocytosis and decreased hematocrit. 2. 2. Individuals were isolated at weaning, paired 3 weeks later for two 30-min encounter periods daily for up to 3 weeks. 3. 3. After 2 days and 1 week encounter periods, subordinates had significantly decreased levels of hemoglobin in the kidney compared to dominants and controls. 4. 4. Subordinates had increased ATP levels in blood after 1, 2 and 3 weeks of encounter, bone marrow erythroid hyperplasia, as well as a substantial increase in the erythropoietin litre and Fe 59 incorporation in spleen and blood.

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