Abstract
Two new prenylated chromones, eriosematins D and E, have been isolated from a dichloromethane extract of the roots of Eriosema tuberosum. Their structures were elucidated by spectroscopic methods, including 2D NMR heteronuclear correlation spectra. In solution, both compounds were shown to be in equilibrium at room temperature; stable derivatives were obtained after acetylation. Both chromones exhibited antifungal activity against Cladosporium cucumerinum and Candida albicans in TLC bioautographic assays.
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