Furostanol glycosides from bulbs of Allium chinense

Abstract

Two new furostanol saponins, named chinenosides II and III, were isolated along with seven known compounds, from the bulbs of Allium chinense G. Don by a combination of silica gel, Diaion HP-20, and octadecylsilanized (ODS) silica gel column chromatographies and preparative HPLC. On the basis of chemical and spectroscopic evidence, the structures of chinenosides II and III were determined to be 26- O- β-glucopyranosyl3 β,26-dihydroxy-(25 R)-5 α-furost-20(22)-en-6-one 3- O- β-xylopyranosyl-(1 → 4)-[ α-arbinopyranosyl(1 → 6)]- β- glucopyranoside and 26- O- β-glucopyranosyl 3 β,26-dihydroxy-(25 R)-5 α-furost-20(22)-en-6-one 3- O- α-arabinopyranosyl(1 → 6)- β-glucopyranoside, respectively.