Abstract
The antihypertensive action of furosemide was evaluated in double-blind studies conducted in three different hospital clinics, by investigators following an identical protocol. The pressure lowering effect of furosemide was compared with that of a placebo in a randomized cross-over study. Both systolic and diastolic pressures were lowered significantly from pretreatment levels in over 50% of patients. No clinically important side effects attributable to furosemide were encountered in this study. Hyperuricemia was encountered in 31 of 44 patients. No significant disturbances of electrolyte balance were noted. Statistical analysis of the pooled data supported the conclusion that furosemide exerts an antihypertensive effect similar to that of other widely used sulfonamide diuretics, and therefore appears to be an effective agent for the treatment of mild to moderate hypertension.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
