Abstract
Flares of asthma were noted by two subjects during the operation of cold-mist vaporizers which, when studied, were found to release yeast-contaminated aerosols. Of 22 additional frequently used devices, 15 were found to raise appreciably indoor fungus levels during the operation; concentrations exceeding 5,000 viable isolates per square meter were not unusual during mist generation. Both filamentous fungi and unicellular forms were found to colonize cold-mist vaporizers and to be released with different temporal patterns that may reflect substrate specificity within these devices. Scrupulous and regular cleansing of accessible inner surfaces was found to markedly decrease but not eliminate mycotic contamination of the aerosols. Decisions to use these devices require an awareness of the potential exposure hazards involved and of the need for more than a casual approach to sanitary maintenance.
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