Abstract
In natural product research, access to new biological sources represents a key element. A particularly large number of biologically active molecules are originating from microorganisms [1]. Very recently, the use of fungal co-culture for activation of silent genes related to metabolite biosynthesis was found successful for the induction of new compounds [2]. For such type of studies a challenge is the localization and identification of the induced metabolites in the confrontation zone where fungi interact at the petri dish level.
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