Abstract
Recent emergence of mycotic burn wound infection as a clinicopathological entity suggested a possible relationship to the use of topical antibacterial therapy. The autopsy incidence of fungal burn wound infection was determined for periods prior to and after the institution of mafenide acetate (Sulfamylon cream) therapy (topically administered) in 1964. There has been a tenfold increase in wound infections due to Phycomycetes and Aspergillus species, since 1964. These two organisms are also the fungi most frequently responsible for clinical mycotic burn wound infection.
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