Abstract
Objective:To investigate the manifestation characteristics of fundus fluorescence angiography (FFA) and its values in diagnosing diabetic retinopathy through comparing direct ophthalmoscopy.Methods:Two hundred fifty patients (500 eyes) who were suspected as diabetic retinopathy and admitted to the hospital between February 2015 and December 2016 were selected. They underwent direct ophthalmoscopy and FFA. The manifestation characteristics of FFA in the diagnosis of diabetic retinopathy were summarized. The two examination methods were compared.Results:In the diagnosis with direct ophthalmoscopy, 375 eyes out of 500 eyes were diagnosed as diabetic retinopathy (75%); there were 74 eyes at stage I, 88 eyes at stage II, 92 eyes at stage III, 83 eyes of stage IV, 28 eyes of stage V and 10 eyes of stage VI. In the diagnosis with FFA, 465 eyes out of 500 eyes were diagnosed as diabetic retinopathy (93%); there were 94 eyes at stage I, 110 eyes at stage II, 112 at stage III, 92 eyes at stage IV, 41 eyes at stage V and 16 eyes at stage VI. The detection rate of diabetic retinopathy using FFA was significantly higher than that using direct ophthalmoscopy (P<0.05). FFA found that 316 eyes had non-proliferative retinopathy (67.96%), 75 eyes had pre-proliferative lesions (16.13%), 149 eyes had proliferative lesions (32.04%), 135 eyes had diabetic maculopathy (29.03%) and 31 eyes had diabetic optic disc lesions (6.67%).Conclusion:The detection rate of diabetic retinopathy using FFA is higher than that using direct ophthalmoscopy. FFA could accurately determine clinical stage. Therefore, it is an important approach in treatment efficacy evaluation and treatment guidance, suggesting a significant application value.
Highlights
Diabetics with a high disability rate and fatality rate has been a common disease affecting the health of people in modern society.[1]
It was reported that the incidence of diabetic retinopathy among patients who have had diabetes for five years was between 49% and 58%
Comparison of examination results: Three hundred and seventy-five eyes were diagnosed as diabetic retinopathy by direct ophthalmoscopy (75%)
Summary
Diabetics with a high disability rate and fatality rate has been a common disease affecting the health of people in modern society.[1] Diabetics is manifested as changes of small vessels and microvessels. Diabetic retinopathy is one of the severest complications in diabetic microangiopathy and the main cause for the blindness of diabetic patients.[2,3] But diabetic retinopathy is difficult to be discovered in the early stage, leading to delayed treatment. It was reported that the incidence of diabetic retinopathy among patients who have had diabetes for five years was between 49% and 58%.4. Pak J Med Sci November - December 2017 Vol 33 No 6 www.pjms.com.pk 1328 early diagnosis of diabetic retinopathy is of great significance to clinical treatment and the improvement of prognosis It was reported that the incidence of diabetic retinopathy among patients who have had diabetes for five years was between 49% and 58%.4 Pak J Med Sci November - December 2017 Vol 33 No 6 www.pjms.com.pk 1328 early diagnosis of diabetic retinopathy is of great significance to clinical treatment and the improvement of prognosis
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