Fundamentals of dual-energy computed tomography and its emerging applications in bladder cancer

Abstract

Nowadays, computed tomography urography and multiparametric magnetic resonance are the most often used imaging techniques in patients with bladder cancer; however, dual-energy computed tomography is making its way into the oncological field. This narrative review article aimed to show the fundamentals of dual-energy computed tomography by outlining its physical principles, techniques, protocols, and postprocessing images to help those who used this cutting-edge technology as the first approach to fully understand its emerging applications in the evaluation of bladder cancer, a field yet to be explored. In particular, we discuss the usefulness of dual-energy computed tomography by focusing on the main images obtained, such as the iodine map, comparing them to the images obtained with conventional computed tomography scans. Dual-energy computed tomography applications may be beneficial for bladder cancer diagnosis, staging, and treatment planning. Nevertheless, its application is limited to its availability in healthcare structures and the training of healthcare personnel who can perform and interpret the scans correctly.