Fundamental and Clinical Study to Evaluate Efficacy of Drakshadya Ghrita on Amlapitta

Abstract

Introduction: Ayurveda's fundamental concepts are based on the Sankhya philosophy of universe creation, according to which man is a Microcosm of a Universe within himself. The introduction of external factors into the human body's internal environment happened by AGNI (Digestive element ). All diseases are caused by to defacement of Agni. (1) Also Amlapitta is a disease caused by a disruption in the Agni level. The classical literature on Amlapitta explains that Amlapitta is such a condition in which Drava guna and Amlaguna (sourness) of Pachak Pitta (Gastric juice ) increase which is normal for Katu rasa (bitter taste). (2) Aacharya Vagbhat in Ashtang Hriday Samhita has explained basic fundaments for Vataj, Pittaj, and Shleshmaj vyadhi chikitsa. Ghrita is par excellent (parma-aushadha)Shamana Dravya for pitta Dosha. (3) Drakshadya Ghrita is the most effective formulation of Ghrit Kalpana mentioned for Amlapitta in Yogratnakar Samhita. (4) Material and Method: Drakshadya Ghrita was prepared by Yogratnakar Formulation. Open Clinical trial of Drakshadya Ghrita was conducted on 45 patients of given inclusion criteria for 10 days with these Assistment criteria - Hrutkanthdaha, Avipaka, Utklesh, Amlodgar, Gaurava, Agnimandya. Observation and Result: Effect on Agnimandya symptoms, Mean 1.06 before treatment which is reduced to 0.11, SD score was 0.96 before treatment which is reduced to 0.31 and Median score was 1 reduced to 0 after treatment after follow-up up with 89.62 % improvement, and there is a statistically significant change (p<0.0001 HS). Discussion: Patients had shown improvement in all the criteria of assessment of Amlapitta. No adverse effect was observed. Thus Drakshadya Ghrita can be recommended for the management of Amlapitta.