Abstract

RAN (Ras-Related Nuclear Protein) is a small GTPase that hydrolyzes GTP and plays a role as a “molecular switch” in cells. According to research using yeast and vertebrate cells, the functions of Ran include two features: for one, controlling nuclearcytoplasm transportation during the interphase stage, for another, mediating spindle assembly in the prophase and the rebuilding of nuclear-membranes during ana- and telophases. Although little is known about the function of Ran in higher plants, according to recent research in modal plants, Ran was found to control the cell cycle in several cell types. Particular research has indicated a relationship between Ran and the auxin signaling pathway. Consequently, the functions of the Ran proteins between different species are essentially conserved and show specificity.

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