Abstract
It has been the intention of the investigations discussed in the following to prepare graded hydroxyapatite/collagen I composites with osteoconductive properties which can be used as coatings for titanium implants or as hone replacements. Functionally graded multiphase calcium phosphate coatings can be applied for biocompatible coatings of metallic implants. Electrochemically assisted TiO 2 - HAP - ACP coatings possess high interface strength, bone like compliancc, and biocompatibility. The integration of collagen I in electrochemically assisted TiO 2 - HAP coatings yields an osteoconductive behavior. Osteoconductive bone replacements can be manufactured from liquid HAP- collagen precursor. The various routes are focused on the formation of structures with graded micro- and macroporosity.
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