Abstract
Presently, antibiotic resistant bacteria (ARB) have been commonly found in environment, such as air, soil and lakes. Therefore, it is urgent and necessary to prepare antimicrobial agents with excellent anti-antibiotic resistant bacteria. In our research, poly-ethylene glycol functionalized molybdenum disulfide nanoflowers (PEG-MoS2 NFs) were synthesized via a one-step hydrothermal method. As-prepared PEG-MoS2 NFs displayed excellent photothermal conversion efficiency (30.6%) and photothermal stability. Under 808 nm NIR laser irradiation for 10 min, the inhibition rate of tetracycline-resistant Bacillus tropicalis and Stenotrophomonas malphilia reached more than 95% at the concentration of 50 μg/mL. More interestingly, the photothermal effect of PEG-MoS2 NFs could accelerate the oxidation of glutathione, resulting in the rapid death of bacteria. A functionalized PEG-MoS2 NFs photothermal anti-antibiotic resistant system was constructed successfully.
Highlights
IntroductionPublisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations
PEG-MoS2 NFs, a bacterial inhibitor with excellent photothermal conversion properties was synthesized by one-step hydrothermal method
The inhibitory effect of PEG-MoS2 NFs was investigated against B. tropicalis and S. maltophilia screened from the lake water
Summary
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. The increase of antibiotic resistant bacteria (ARB) had a great impact on public health [1,2,3,4]. ARB can be continuously spread through the medium of animal excreta, water, and air. More than a hundred kinds of resistance genes can be detected in the samples collected from livestock and poultry breeding sites. The antibiotic resistant genes of these antibiotic resistant bacteria may be transferred from environmental host bacteria to pathogens through gene horizontal transfer, or from pathogens to primary host bacteria in the environment [5,6,7,8]. It is urgent and necessary to explore and develop non-antibiotic antibacterial agents
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