Abstract
The detection of biologically relevant analytes at ultra-low concentrations using the unique physicochemical properties of metal nanoclusters (MNCs) has emerged as a frontier research area in recent decades. In this chapter, we discuss the most recent emerging trends in MNC-based biosensing applications. In particular, we have summarized the biosensing strategies with two key features of the MNCs. These are MNC-based (i) optical biosensors and (ii) electrochemical biosensors. In optical biosensing applications, both the absorbance as well as the photoluminescence properties of MNCs are frequently explored and are therefore discussed in the chapter with special emphasis on the detection of various diseases and bacteria. Finally, the pros and cons as well as discussions about further directions in designing MNC-based smart biosensors is also presented.
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