Abstract
Abstract Mesostructured cellular foam (MCF) materials were synthesized by microemulsion followed by functionalization with glucose or glutaraldehyde. Successful surface modification was confirmed by Fourier transform infrared, X-ray small-angle diffraction, and nitrogen sorption measurements. The effect of surface chemistry of MCF on the loading and release of streptomycin sulfate was studied in detail. Results indicated that grafting with either glucose or glutaraldehyde cannot only increase the loading amount of drug from 5% to 25% but also change the drug release profile significantly. This work provided an excellent example of controlling drug release by varying the surface chemistry of the materials.
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