Abstract
Functionalized magnetic composites based on block copolymers poly(succinimide)-b-poly(ethylene glycol) have been obtained by immobilization of biotin on composites particles via activation with 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide hydrochloride (EDAC). Dynamic light scattering measurements showed that hydrodynamic mean diameters of the functionalized particles were about 500nm and indicate their potential to be formulated as injectable suspensions. These particles exhibit a superparamagnetic behavior and good magnetic saturation, characteristics that recommend them for magnetic separation techniques. Blood coagulation assays indicated that functionalized magnetic composites did not induce thrombogenic reactions in contact with blood.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
