Functional state of the heart, perxifcation oxidation of proteins and the activity of antioxidant enzymes in the blood of sexually nature rats when introducing food supplements

Abstract

The bioelectric activity of the heart, pro- and antioxidant processes in the blood of adult rats after the introduction of dietary supplements: glutamate and sodium benzoate, dye tartrazine were investigated. Consumption of sodium glutamate, sodium benzoate, tartrazine, each individually, by adult rats leads to a breakdown in a heart rate, a decrease in the duration of electrical diastole of the heart, a distortion of the P-wave potential, an increase in heart rate variability, which indicates the increased activity of cholinergic nerve fibbers involved in the regulation of the cardiac activity. In sexually mature animals, the consumption of sodium glutamate does not affect the equilibrium state in the peroxidation system – the antioxidant protection in the blood, while dye tartrazine, which is consumed with food for a long time, initiates the process of protein peroxidation and causes to suppress in the blood of sexually mature animals.