Abstract
Microelectrode techniques were used to test the extent of functional transverse interconnections of specialized conduction fibers within the exposed canine bundle of His and within the right and left bundle branches. It was demonstrated that the activation sequence of the bundle branches during extracellular stimulation of the proximal His bundle was the same as during intracellular stimulation of single bundle of His cells at various locations within the His bundle. The activation sequence was unmodified by partial transection of the His bundle at numerous sites. In cases where activity was initiated in one bundle branch, rapid conduction proceeded across a short segment of isolated distal His bundle to the contralateral bundle branch. We conclude that, when intra-His bundle conduction speed is normal, functional transverse interconnections within the canine bundle of His result in propagation of a single, uniformly advancing wave front, without longitudinal dissociation being present.
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