Abstract

A Rare Case of Tamoxifen-Induced ThrombocytopeniaAnurag Pathak, Sushil Kiran Kunder, A Avinash, Navin Patil, N Karthik Rao

Highlights

  • During the last 50 years it has become clear that several of the degenerative and infectious diseases in man, are greatly affected by the nutritional habits of individual populations over time

  • The milk’s ability to inhibit platelet aggregation and reduce thromboxane B2 (TXB2) production could be attributed to its high content in antioxidant substances and poly-unsaturated fatty acids, when originating from grazing goats in semi-mountainous shrublands

  • 2011 have recently showed that that cow’s and goat’s milk possess considerable inhibitory ability regarding platelet aggregation, an ability that is well-correlated to their total antioxidant strength. Based on these data we embarked on a study of the ability of goat milk from Capra prisca, a Greek indigenous herd, to inhibit human platelet ex vivo and washed rabbit platelet aggregation in vitro, as well as to inhibit in parallel the production of TXB2 from human platelets. In these same experiments we studied the action of ascorbic acid, linoleic and linolenic acid on the various experimental settings used

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Summary

Introduction

During the last 50 years it has become clear that several of the degenerative and infectious diseases in man, are greatly affected by the nutritional habits of individual populations over time. It has further been shown that the nutritional patterns that have been established in the Mediterranean basin over thousands of years exert a protective effect, concerning such diseases, on the population (Willett et al, 1995). Studies analysing the protective effect of the Mediterranean diet indicate that this diet contains large amounts of the necessary vitamins, trace elements, polyunsaturated fatty acids and poly-phenols; all these substances have a high anti-oxidative potential and function as detoxifiers modifying the immune mechanisms of the organism, reduce the intense proinflammatory reactions and function towards. Goat milk and its respective dairy products have an important place in human nutrition; in addition, it is considered an important food, especially for children, as it can fully substitute cow’s milk (Hanlein, 2001).

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