Functional properties of hemostasis in piglets after short-term overheating against the background of corrective action

Vladimir V Zaitsev,Marina V Mekhanikova,Svetlana V Shestakova,Tatyana P Ryzhakina,D Fayzrakhmanov,F Nezhmetdinova,R Shaydullin,B Ziganshin

doi:10.1051/bioconf/20201700169

Vladimir V Zaitsev, Marina V Mekhanikova + Show 6 more

Open Access

https://doi.org/10.1051/bioconf/20201700169

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Abstract

Catosal is considered to be a highly effective bio-stimulator. It showed his properties in animals, realizing the stimulation of their tissues and organs. The purpose of this research is to determine the effect of Catosal on hemostatic parameters in piglets that experienced overheating. 58 piglets at the age of 2.5 months, which belonged to a large white breed, were taken into work. All animals as a result of an accidental emergency shutdown of the air conditioning system in the pigsty suffered overheating for 3 hours. These animals were randomly divided into two comparable groups. One was named experimental; the other was called control 1. Pigs of the experimental group (21 heads) received intramuscular injections of 2.5 ml of Catosal daily for 5 consecutive days, from the next day after an overheating episode. The control group 1 consisted of piglets with a total number of 21. After an overheating episode, they were under the usual conditions of a pigsty and did not receive any effects. In experimental piglets and piglets of the control group 1, all indicators were recorded in the outcome and after 30 days. Control group 2 consisted of 32 completely healthy piglets that were kept under standard conditions of a pigsty for their entire lives. They were examined once. Catosal injections in the observed piglets after overheating led to a decrease in spontaneous and stimulated platelet aggregation to normal levels. Against the background of the use of Catosal in the piglets that made up the experimental group, a weakening of hemocoagulation was found, which improved blood circulation in their tissues. Piglets of control group 1 showed an increase in platelet aggregation and blood coagulation. This had a very negative effect on hemorheology in them and weakened their metabolism. We can assume that in piglets after overheating, in the absence of optimizing effects, hemostasis is activated. This adversely affects the course of microcirculation and inhibits growth. Injections in piglets after overheating of the Catosal lead to a weakening of hemocoagulation and platelet activity to optimum values. This normalizes the course of microcirculation in the internal organs of animals.

Highlights

In the modern world, pig breeding is an actively developing highly efficient branch of agriculture
Nowadays pig breeding demonstrates a serious need for further accumulation of knowledge on aspects of the physiology of piglets [2]
It changes its settings on the intake of many substances. The stronger this background changes the metabolism, the result of a change of blood counts. This is true for hemostasis, which is able to regulate the condition of the animal

Summary

Introduction

Pig breeding is an actively developing highly efficient branch of agriculture It provides a significant part of the world's population with highly nutritious food products – lard and meat [1, 2]. In view of the importance of pig breeding, its practitioners set the task of intensifying it by accelerating the rearing of young animals and achieving maximum preservation of the livestock [3]. This is possible to achieve through the use of new approaches to feeding and keeping [4]. Due to the serious physiological significance and the possibility of rapid violation of indicators, they are paying more and more attention in studies under standard and model conditions [8]

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