Functional Network of Neurocognitive Development in Correlations of BOLD Signals

Abstract

Blood Oxygen Level Dependent (BOLD) fMRI is widely used for non-invasive brain mapping and neuroimaging. Despite the challenges, significant advancements have been made in empirically explaining several (BOLD) signal features. Before applying functional connectivity measures to assess the (BOLD) signal, preprocessing is required. Different stimuli produced by a regular periodic oscillation pulse and propagation loops were applied to generate the (BOLD) signal. The fundamentals of the brain and cognitive development are being highlighted through functional connectivity in a unique approach. In this work, we present an approach that analyzes variations in (BOLD) connectivity over time. Our approach emphasizes the temporal or spatial aspects however, simultaneous co-activation events may trigger (BOLD). Our findings show the measures to assess Functional Connectivity (FC) through Pearson’s correlation to describe FC. (BOLD) responses are used in a voxel-wise linear model with an estimation of the maximum likelihood to get the regressors’ correlated components.