Functional Near infrared spectroscopy (fNIRS) to investigate language patterns development over ages

Abstract

Event Abstract Back to Event Functional Near infrared spectroscopy (fNIRS) to investigate language patterns development over ages Julie Tremblay1*, Anne Gallagher1, Berta González-Frankenberger1, 2, Natacha Paquette1, 3, Phetsamone Vannasing1, Olivia Florea1, 3, Renée Béland4, Franco Lepore1, 5 and Maryse Lassonde1, 3 1 Ste-Justine Hospital Research Center, Canada 2 Universidad Nacional Autónoma de México, Mexico 3 University of Montréal, Psychology, Canada 4 University of Montréal, Orthophony, Canada 5 University of Montréal, Canada Neuroimaging techniques such as fMRI have been the object of many studies aiming to localise language areas and find a replacement for the amobarbital procedure. Although good results have been obtained in adults, fMRI is not always conclusive in children, mainly because fMRI scanner is a stressful environment for young children and it is difficult to verify if they perform the task correctly. Functional near infrared spectroscopy (fNIRS) seems to be a good alternative to investigate language, especially in paediatric populations. We recorded fNIRS data during a verbal fluency task performed aloud by 41 individuals. Participants were divided in 4 groups: 1 - younger children (3-6 years (n=10)), 2- older children (7-10 years (n=10)), adolescents (11-16 years (n=12)) and adults (18 years + (n=9)). A method to detect and correct abrupt variations due to movement artefact developed by our group has been applied on individual data. Then, modified Beer Lambert Law was applied to estimate variations in HbO2 and HbR concentrations. For all groups an increase in HbO2 concentration was seen during the language task in Broca's area along with a weaker activation in the homologous area. The effect of age on hemodynamic response was further assessed using a mixed design ANOVA with Hemisphere as a within-subject factor and age groups as the between-subject factor. Results revealed a significant main effects for factors Group (F(3, 37) = 5.42, p < 0.05) indicating an increase of amplitude with age and a main effect for hemisphere (F(1, 37) = 35.63, p < 0.001) indicating a higher HbO2 concentration in the left hemisphere than in the right hemisphere in all groups. fNIRS is a good technique to investigate language dominance in participants from as young as 3 years old. Finally, our results suggest that our movement artefact rejection and correction tool increases significantly the NIRS data quality especially in young participants. Keywords: Language, Children, Broca's area, fNIRS, verbal fluency Conference: XII International Conference on Cognitive Neuroscience (ICON-XII), Brisbane, Queensland, Australia, 27 Jul - 31 Jul, 2014. Presentation Type: Oral Presentation Topic: Language Citation: Tremblay J, Gallagher A, González-Frankenberger B, Paquette N, Vannasing P, Florea O, Béland R, Lepore F and Lassonde M (2015). Functional Near infrared spectroscopy (fNIRS) to investigate language patterns development over ages. Conference Abstract: XII International Conference on Cognitive Neuroscience (ICON-XII). doi: 10.3389/conf.fnhum.2015.217.00078 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 19 Feb 2015; Published Online: 24 Apr 2015. * Correspondence: Mrs. Julie Tremblay, Ste-Justine Hospital Research Center, Montréal, Canada, julie.tremblay3@gmail.com Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Julie Tremblay Anne Gallagher Berta González-Frankenberger Natacha Paquette Phetsamone Vannasing Olivia Florea Renée Béland Franco Lepore Maryse Lassonde Google Julie Tremblay Anne Gallagher Berta González-Frankenberger Natacha Paquette Phetsamone Vannasing Olivia Florea Renée Béland Franco Lepore Maryse Lassonde Google Scholar Julie Tremblay Anne Gallagher Berta González-Frankenberger Natacha Paquette Phetsamone Vannasing Olivia Florea Renée Béland Franco Lepore Maryse Lassonde PubMed Julie Tremblay Anne Gallagher Berta González-Frankenberger Natacha Paquette Phetsamone Vannasing Olivia Florea Renée Béland Franco Lepore Maryse Lassonde Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.