Abstract
Functional magnetic resonance imaging (fMRI) is an exciting new technique that permits mapping of subtle changes in local blood oxygenation in the brain with excellent spatial and temporal resolution, thus improving on the resolution of other functional imaging modalities, including positron emission tomography (PET), rCBF, and SPECT. Functional MRI is also noninvasive and repeatable, and it does not require radioisotopes. Substantially more accurate mapping of brain structure to function is made possible at the individual subject level because there is intrinsic coregistration of anatomic and functional images with resolution on the order of millimeters.
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