Abstract

By virtue of the recently accumulated microbial genomic sequence data, we can utilize this large amount of information for predicting and understanding microbial gene functions and microbial life through comparative analysis of variously related genomes. Here, I introduce basic concepts and issues in microbial comparative genomics including ortholog analysis and core genome analysis, and introduce our approach to large-scale comparative genomics focusing on our database, Microbial Genome Database for Comparative Analysis (MBGD) and related methods and tools.

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