Abstract
The paper summarizes data about the structure and function of the endothelium of the brain vessels, heart, lungs, liver and kidneys. Endothelial cells have important functions, the implementation of which depends on the hemodynamic and cellular microenvironment of a particular organ or tissue. The manifestations of endothelial dysfunction, changes in the direction and intensity of the formation of individual endothelial factors due to the heterogeneity of the endothelium, and depend on the structure, organization and biochemical functions of the authority. Understanding the differences in morphology, ultrastructure, gene expression and function of various subpopulations of endothelial cells may be of therapeutic relevance for regenerative medicine, cell therapy of endothelial dysfunctions and ischemic revascularization.
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