Abstract
Research Investigation of enteric neurobiology and development of the enteric nervous system. Neuro‐immunology and the gut: characterization of the interactions between the central nervous system, enteric nervous system and immune system. Evaluation of the role of early life events in the development of functional gastrointestinal disorders. Intervention evelopment of multicenter, controlled studies aimed at evaluating epidemiology, pathophysiology and treatment of functional bowel disorders. Creation of a tissue bank for children with enteric neuromuscular disorders. Validation of the Rome II diagnostic criteria at the general practitioner and specialty level. Education Train physicians and researchers in performing motility, sensory, and laboratory assessment in the field of enteric neuromuscular disorders. Educate primary care physicians in the evaluation and treatment of GER and other functional bowel disorders. Educate care providers on the high incidence of enteric neuromuscular disorders and the special needs of children with neurologic handicaps.
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