Abstract
Pepper vein banding virus (PVBV) is a distinct species in the Potyvirus genus which infects economically important plants in several parts of India. Like other potyviruses, PVBV encodes multifunctional proteins, with several interaction partners, having implications at different stages of the potyviral infection. In this review, we summarize the functional characterization of different PVBV-encoded proteins with an emphasis on their interaction partners governing the multifunctionality of potyviral proteins. Intrinsically disordered domains/regions of these proteins play an important role in their interactions with other proteins. Deciphering the function of PVBV-encoded proteins and their interactions with cognitive partners will help in understanding the putative mechanisms by which the potyviral proteins are regulated at different stages of the viral life-cycle. This review also discusses PVBV virus-like particles (VLPs) and their potential applications in nanotechnology. Further, virus-like nanoparticle-cell interactions and intracellular fate of PVBV VLPs are also discussed.
Highlights
The genus Potyvirus, named after its type species, Potato virus Y (PVY) [1], in the family Potyviridae is the largest group of plant RNA viruses that are economically very important [2]
The proteins encoded by potyviruses are multifunctional, have multiple interacting partner proteins and participate in various events of the viral life cycle
It was demonstrated that the nuclear fractions of pepper vein banding virus (PVBV)-infected plant cells contained viral protein genome linked (VPg)-Pro which was capable of Mg2+ -dependent DNase activity, by virtue of the protease domain involving the Asp 81 as an essential residue required for metal ion-binding
Summary
The genus Potyvirus, named after its type species, Potato virus Y (PVY) [1], in the family Potyviridae is the largest group of plant RNA viruses that are economically very important [2]. Potyviruses cause significant loss to agricultural productivity by infecting economically important crops—especially those belonging to the Cucurbitaceae, Solanaceae, Cruciferae and Compositae family [3,4]. Apart from infecting agriculture crops, potyviruses have wild plant hosts as well [5,6]. A major bottleneck in its cultivation was crop loss due to infection by viruses, by pepper vein banding virus (PVBV) [3,4]. PVBV infects Solanaceae plants such as bell-pepper (Capsicum annuum) and chili (Capsicum frutescens) and pose a major threat to the agriculture. Turnip mosaic virus (TuMV) known as PIPO (pretty interesting potyviridae ORF) [11] which is which is formed by transcriptional slippage at the conserved. 6-7 formed by transcriptional slippage at the conserved G1-2 A6-7 motif in the P3 nucleotide sequence. Group of potyvirus, known as PISPO (pretty interesting sweet potato potyvirus [12,13], group of potyvirus, known as PISPO (pretty interesting sweet potato potyvirus ORF) [12,13], formed totranscriptional the transcriptional slippage atGthe
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
