Abstract
Taking into account the ever-increasing role of prevention in modern conditions, a comprehensive understanding of the morph physiological and chronobiological organization of human life is necessary, which is most optimal for living in specific environmental conditions, in other words, the conditions for the formation of population health and its pathological deviations due to factors that exist in the very organism, as well as acting on it from the outside. The process of cleansing the body of denatured, aged proteins occurs in many organs, primarily in the liver. Degradation processes in a cell can both recognize proteins to be degraded and begin degradation, but these processes must be selective, since there is significant heterogeneity in the rates of degradation of various proteins in one cell. Proteases are usually required for the implementation of catabolic processes, and apparently, lysosomal and extra-lysosomal proteases are involved in the catabolism of cellular proteins. The concentration of total protein and its fractions in the blood plasma in people living in various districts of the Kyzylorda region does not depend on the severity of the action of extreme factors characteristic of the Aral Sea zone.
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