Abstract

The brain is arguably the most important organ in the human body. It controls and coordinates actions and reactions, allows us to think and feel, and enables us to have memories and feelings. Three brain structures namely the hippocampus, amygdala and prefrontal cortex help the brain determine what is stressful and how to respond. Depression in teenagers is a very serious medical problem that leads to long-lasting feelings of sadness along with a loss of interest in once enjoyed activities. Neuroimaging is the use of various techniques to either directly or indirectly image the structure and function of the nervous system. Magnetic resonance imaging (MRI) are two in types, viz., structural and functional imaging. Functional neuroimaging has greatly helped in understanding the cognitive functions of the brain and its impact on mental health and human behaviour. This paper describes the different types of neuroimaging techniques and its needed software configurations with statistical parametric mapping. This paper also elaborates the basic operations and MATLAB activities and it compare the at-risk and control group depression imaging fMRI analysis techniques with its snapshots.

Highlights

  • Human intelligence can be broadly defined as the capacity to understand complex ideas, adapt effectively to the environment and engage in complex reasoning

  • To better understand the neurobiological underpinnings of major depressive disorder (MDD) early in development, this study examined brain function in response to emotional faces in adolescents with MDD and healthy (HC) adolescents using functional magnetic resonance imaging

  • In the first phase of the project, a set of four sample functional magnetic resonance imaging (fMRI) dataset are taken from online medical repository which consists of several BOLD signals for depression levels where those data are pre-processed using Statistical Parametric Mapping (SPM) under MATLAB

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Summary

Introduction

Human intelligence can be broadly defined as the capacity to understand complex ideas, adapt effectively to the environment and engage in complex reasoning. The brain is arguably the most important organ in the human body. It controls and coordinates actions and reactions, allows us to think and feel, and enables us to have memories and feelings. The cerebellum is below and behind the cerebrum and is attached to the brain stem It controls motor function, the body's ability to balance, and its ability to interpret information sent to the brain by the eyes, ears, and other sensory organs. Three brain structures namely the hippocampus, amygdala and prefrontal cortex help the brain determine what is stressful and how to respond. Teen depression affects the way a teen thinks, feels, behaves, and can lead to significant emotional, functional, and physical problems

Neuro Imaging
Neuro Imaging Techniques
Statistical Analysis
Statistical Parametric Mapping
Basic Operations
MATLAB
Amygdala Portions
Realign
Coregister
Segment
Normalise
Smooth
Fmri Analysis and Its Model Specification
Snapshots
Conclusion
Full Text
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