Abstract
THE purpose of this paper is to present observations on the effects of radiation in patients who have been treated with radioactive iodine. Attention has been directed toward: 1) the metabolism of the thyroid cells as measured by tracer doses of radioactive iodine before and after radiation therapy; and 2) the histologic features of cellular damage of the thyroid and the regenerative processes that may take place after large doses of radioactive iodine. It has been adequately shown that a large dose of radioactive iodine impairs the functional capacity of the human thyroid (1–22). This principle has been employed in the treatment of some patients with Graves' disease (1–4, 6, 8, 9, 17–19, 21–35), others with functioning carcinomas of the thyroid (29–35) and still others with heart disease accompanied by normal thyroid function (17, 19, 28). Although a large number of patients with thyrotoxicosis have been treated with radioactive iodine, relatively few observations have been published on the nature of the...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: The Journal of Clinical Endocrinology & Metabolism
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
