Abstract
Chemical transmitters of nervous impulses play an important role in the physiological functions of the brain [1–3]. The role of mediator systems in the development of pathological processes in the CNS and, in particular, in,the genesis and course of epilepsy is possible. This hypothesis, together with great advances in the search for the pharmacological agents responsible for transmission of nervous impulses [2, 3], has encouraged the study of the role of chemical mediators in the pathogenesis of epilepsy and the effect of drugs modifying their functions on the course of the epileptic process. This, in turn, must benefit the rational search for antiepileptic drugs among substances interacting with mediator systems.
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