Function and inhibition sensitivity of the N-terminal segment of surfactant protein B (SP-B1-25) in preterm rabbits

Abstract

BACKGROUNDSurfactant protein B (SP-B) is an essential component of pulmonary surfactant, but shorter SP-B sequences may exert equivalent surface activity.METHODSWe synthesised a peptide based on the amino-terminal domain of SP-B...