Abstract

IntroductionInfectious mononucleosis is a clinical syndrome most commonly associated with primary Epstein-Barr virus infection. The majority of patients with infectious mononucleosis recovers without apparent sequelae. However, infectious mononucleosis may be associated with several acute complications. In this report we present a rare case of esophageal rupture that has never been described in the literature before.Case presentationWe present the case of an 18-year-old Caucasian man affected by severe infectious mononucleosis complicated by fulminant hepatic failure, splenic rupture and esophageal necrosis.ConclusionsAlthough primary Epstein-Barr virus infection is rarely fatal, fulminant infection may occur - in this case leading to hepatic failure, splenic rupture and esophageal necrosis, subsequently making several surgical interventions necessary. We show here that infectious mononucleosis is not only a strictly medical condition, but can also lead to severe surgical complications.

Highlights

  • Infectious mononucleosis is a clinical syndrome most commonly associated with primary Epstein-Barr virus infection

  • Case presentation: We present the case of an 18-year-old Caucasian man affected by severe infectious mononucleosis complicated by fulminant hepatic failure, splenic rupture and esophageal necrosis

  • Conclusions: primary Epstein-Barr virus infection is rarely fatal, fulminant infection may occur - in this case leading to hepatic failure, splenic rupture and esophageal necrosis, subsequently making several surgical interventions necessary

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Summary

Conclusions

Primary EBV infection is rarely fatal, fulminant infection may occur - in this case leading to hepatic failure, splenic rupture and esophageal necrosis that required surgical interventions. That in rare situations infectious mononucleosis is a medical condition but can lead to severe complications including the need for surgical intervention. This case is an example of successful interdisciplinary management of complicated fulminant infectious mononucleosis in an otherwise healthy 18-year-old Caucasian man. Consent Written informed consent was obtained from the patient for publication of this case report and any accompanying images.

Introduction
Discussion
Smith JN Jr
Findings
14. Jenson HB
Okano M
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