Abstract
The advent of tumor necrosis factor-a antagonists has revolutionized the treatment of various chronic diseases including Crohn disease and rheumatoid arthritis. The use of these drugs is ever expanding with recent reportsof their efficacy in other chronic diseases such as psoriasis. However, with increased use of these drugs, there have been increasing reports of infectious complications seen in patients who have received tumor necrosis factor-a antagonists. We report a case of cytomegaloviral pneumonia in a patient who received multiple immunosuppressive agents including tumor necrosis factor-a antagonists for Crohn colitis. The case illustrates the need for aggressive diagnostic as well as therapeutic measures in patients treated with anticytokine agents who are admitted to the hospital with potential infectious complications.
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