Fütterungsversuche zur biosynthese des damascenins in Nigella damascena L. : 6. Mitteilung über das damascenin

Abstract

Damascenine was shown to be synthesized in the seeds of Nigella damascena via the shikimic acid pathway. [U- 14C]Glucose, [ carboxy- 14C] shikimic acid, [ carboxy- 14C] anthranilic acid, and [ carboxy- 14C] 3-methoxy-anthranilic acid were incorporated in damascening. When these acids labelled in the carboxylic group were fed, radioactivity was also recovered in the carboxylic group of damascenic acid. All the three methyl groups in damascenine can arise from administered [ Me- 14C] methionine. The N-methyl group showed a labelling three to four times as high as the O-methyl and ester methyl groups.