Abstract
In the March 8 New Engl. J. Med., researchers report that although some Parkinson's patients who received intracranial fetal cell injections experienced significant improvement, several patients were troubled by significant side effects. This study, which is the first that compares the effects of transplantation to that of control sham surgery, is important in that it specifically proves specific graft-induced clinical improvements. The severe dyskinesias developed by five of the twenty transplant patients, however, indicate a need to better tailor and regulate transplantation material. The second placebo-controlled fetal cell transplantation study at the University of South Florida will be completed next year. LO
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