Abstract

Fruit pods contain various beneficial compounds that have biological activities and can be used as a source of pharmaceutical and nutraceutical products. Although pods or pericarps are usually discarded when consuming the edible parts of fruits, they contain some compounds that exhibit biological activities after extraction. Most fruit pods included in this review contain polyphenolic components that can promote antioxidant effects on human health. Additionally, anti-inflammatory, antibacterial, antifungal and chemopreventive effects are associated with these fruit pod extracts. Besides polyphenolics, other compounds such as xanthones, carotenoids and saponins also exhibit health effects and can be potential sources of nutraceutical and pharmaceutical components. In this review, information on fruit pods or pericarp of Garcinia mangostana, Ceratonia siliqua, Moringa oleifera, Acacia nilotica, Sapindus rarak and Prosopis cineraria is presented and discussed with regard to their biological activity of the major compounds existing in them. The fruit pods of other ethno- botanical plants have also been reviewed. It can be concluded that although fruit pods are considered as being of no practical use and are often being thrown away, they nevertheless contain compounds that might be useful sources of nutraceutical and other pharmaceutical components.

Highlights

  • A nutraceutical is defined as any substance that is food or a part of food that provides medical or health benefits, for the prevention and treatment of diseases [1]

  • This review focuses on bioactive compounds or phytochemicals of fruit pods with beneficial health effects that have potential pharmaceutical and nutraceutical applications

  • This review focuses on the beneficial effects of bioactive compounds from fruit pods through the review by available in-vitro, pre-clinical and/or human trial studies in the related literature

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Summary

Introduction

A nutraceutical is defined as any substance that is food or a part of food that provides medical or health benefits, for the prevention and treatment of diseases [1]. Plant extracts can be toxic and contain excessive lethal constituents such as aristolochic acids, pyrrolizidone alkaloids, benzophenanthrine alkaloids, viscotoxins, saponins, diterpenes, cyanogenetic glycosides and furanocoumarins [6] These compounds can affect human health since nutraceutical products, unlike pharmaceutical products, are not as well regulated and are commonly consumed without supervision or medical guidance. In between the mesocarp and endocarp, there is a part called the aril or placenta of the seed that can be consumed This part is usually white in color and juicy as an attractant to animals in order for the plant to grow diversely [11]. This review focuses on bioactive compounds or phytochemicals of fruit pods with beneficial health effects that have potential pharmaceutical and nutraceutical applications. This review focuses on the beneficial effects of bioactive compounds from fruit pods through the review by available in-vitro, pre-clinical and/or human trial studies in the related literature

Garcinia mangostana
Ceratonia siliqua
Moringa oleifera
Acacia nilotica
Sapindus rarak
Prosopis cineraria
Other Ethnobotanicals
Findings
Conclusions
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