Abstract

The frontispiece shows the casein kinase 2 (CK2), cyclin-dependent kinase 2 (CDK2), HIV-1 protease (HIV-1 PR) and their inhibitors. Jindřich Fanfrlík and co-workers discuss the latest developments in modern quantum mechanics (QM)-based computer-aided drug design, especially using semiempirical QM methods in their Minireview on page 921 ff.

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