Frontispiece: Recent Progress in Fluorescence Signal Design for DNA‐Based Logic Circuits

Abstract

DNA computing has the potential to execute orders of magnitude more powerful functions than traditional silicon circuitry and has a wide range of applications in medical diagnosis, in situ analysis, and artificial intelligence. However, since nucleic acids cannot present detectable signals by themselves, designing suitable signal modules is becoming a crucial issue, as important as the design of the DNA sequence. Numerous signal strategies, especially fluorescent ones, have been proposed to realize both basic DNA gates and advanced DNA circuits. For more information see the Minireview by Q. Yang et al. on page 5389 ff.