Abstract
Ene-reductases (ERs) are valuable biocatalyst that engages in stereospecific reduction of activated C=C bonds and exhibit increased prominence in the production of pharmaceutical ingredients, agrochemical synthons, and fine chemicals. In addition to traditional biocatalysis, ERs evolved in multi-enzyme cascades, chemoenzymatic, photoenzymatic, photoelectrochemical, single-reduction chemistry, and radical-mediated transformation which unravels its versatility and multifaceted nature in organic transformations. For more information, see the Review by T. Gandhi, D. Maiti et al. (DOI: 10.1002/chem.202103949)
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