Abstract
Mol. Nutr. Food Res. 2020, 64, 2000341 DOI: 10.1002/mnfr.202000341 Xanthohumol (XN), a flavonoid from hops (Humulus lupulus), and its hydrogenated derivatives, α,β-dihydroxanthohumol (DXN) and tetrahydroxanthohumol (TXN) decrease hepatic cholesterol by enhancing de novo synthesis of bile acids and decrease ceramide content in liver and hippocampus. The subsequent amelioration of obesity-induced metabolic and neurocognitive impairments suggests that XN, DXN, and TXN may mitigate metabolic syndrome by targeting the liver-brain axis. This is reported by Ines L. Paraiso, Johana S. Revel, Jaewoo Choi, Cristobal L. Miranda, Parnian Lak, Chrissa Kioussi, Gerd Bobe, Adrian F. Gombart, Jacob Raber, Claudia S. Maier, Jan F. Stevens in article 2000341.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
