Abstract
The Front Cover represents the lysis of a bacterial cell promoted by a sugar-based, membrane-binding bactericide – an illustrative example of one of the three main classes of sugar-derived antibacterials. Some of the most promising compounds published between 2016 and 2022 are covered in this review, where their design, synthesis, and biological evaluation are concisely explored. Based on the promising bioactivities and innovative mechanisms of action of these compounds, carbohydrates are highlighted as starting points for the development of new solutions for the emerging problem of antimicrobial resistance. More information can be found in the Review by A. M. de Matos.
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