Abstract
The front cover picture illustrates the application of Zn-complex as a key catalyst for enantioselective hydrosilylation of cyclic imines. As the replacement of platinum-group metals is currently an interesting challenge in catalysis, a promising alternative in asymmetric hydrosilylation, is to use environmentally benign and easily accessible chiral Zn-based catalysts. I. Węglarz, K. Michalak and J. Mlynarski show that in situ generated zinc-ProPhenol complex with silane affords pharmaceutically relevant enantioenriched 2-aryl-substituted pyrrolidines in high yields and with excellent enantioselectivities (up to 99% ee). Details can be found in the communication by Jacek Mlynarski and co-workers (I. Węglarz, K. Michalak, J. Mlynarski, Adv. Synth. Catal. 2021, 363, 1317–1321; DOI: 10.1002/adsc.202001043).
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