Abstract
The front cover picture illustrates the application of Zn-complex as a key catalyst for enantioselective hydrosilylation of cyclic imines. As the replacement of platinum-group metals is currently an interesting challenge in catalysis, a promising alternative in asymmetric hydrosilylation, is to use environmentally benign and easily accessible chiral Zn-based catalysts. I. Węglarz, K. Michalak and J. Mlynarski show that in situ generated zinc-ProPhenol complex with silane affords pharmaceutically relevant enantioenriched 2-aryl-substituted pyrrolidines in high yields and with excellent enantioselectivities (up to 99% ee). Details can be found in the communication by Jacek Mlynarski and co-workers (I. Węglarz, K. Michalak, J. Mlynarski, Adv. Synth. Catal. 2021, 363, 1317–1321; DOI: 10.1002/adsc.202001043).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
