Abstract
The front cover image illustrates the oxidation of primary aromatic and aliphatic allylic alcohols to valuable aldehydes catalyzed by a recombinant aryl-alcohol oxidase of Pleurotus eryngii P34. This versatile enzyme demonstrates high stability against the by-product of the reaction, H2O2, and in the presence of organic solvents. After reaction optimization, a space-time-yield of 9.5 g piperonal/l/h was achieved on a preparative scale. The produced aldehydes are of great interest as fragrances or building blocks in the synthesis of pharmaceuticals. Further details can be found in the Research Article by Urlacher and co-workers (N. Jankowski, K. Koschorreck, V. B. Urlacher, Adv. Synth. Catal. 2022, 364, XXXX–XXXX; DOI: 10.1002/adsc.202200381)
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