Abstract
Work with the elements of nature: Our building block, maytansinol, represented as a constellation of stars, is the main protagonist of the story. A ray of light coming out from it demonstrates how different moieties can be attached to it, opening new horizons. As maytansinoids show a destabilising effect on microtubules, we represent the latter by trees. The tree trunk is a microtubule, from which the tubulins are disassembling into the leaves. The TubInTrain logo in the corner represents the H2020-MSCA-ITN-2019 network that made this interdisciplinary investigation possible. More information can be found in the Research Article by S. Pieraccini, D. Passarella and co-workers. (DOI: 10.1002/chem.202203431). Created with BioRender.com.
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