Front Cover: Efficient Imidazolium‐Biomolecule Interaction‐Assisted Amplified Quenching for Ultrasensitive Detection of Heparin (Chem. Asian J. 18/2022)

Abstract

A micelle-based efficient sensing approach, exhibiting stronger amplified fluorescence quenching by introducing imidazolium capable of enhancing affinity for heparin (HP), is described. The pyrene aggregates in the micelle provide an efficient sensing platform for amplified quenching, and the C2 proton of imidazolium on the micelle surface attracts HP very effectively, as if black holes exert pressure on their environment. A micelle-based fluorescent sensor with these features detects HP more sensitively than conventional fluorescent sensors with aliphatic ammonium. More information can be found in the Research Article by Seoung Ho Lee et al.